Brandon Aiyuk's acceleration and ball-tracking skills could spell trouble for Kansas City's middling safeties, but first the Niners need to keep DL Chris Jones off of Brock Purdy.
WR Deebo Samuel had no issues with his injured shoulder and helped push the 49ers into the Super Bowl.
Michael Rathburn presents NFL Odds and Key Line Moves for Super Bowl LVIII Kansas City Chiefs vs. San Francisco 49ers
Jim Coventry reacts to the Conference Championship games, including an incredible comeback win by the 49ers.
Facing a tough defense with the bull's eye on him, Sunday's showdown with Buffalo will help clarify just how good Rashee Rice can be.
The top seeds begin their playoff adventure this week. See where they and their opponents rank.
Michael Rathburn presents NFL Picks and Key Line Moves for Divisional Round Playoff Weekend.
Chiefs TE Travis Kelce is cleared from the final injury report and may get the 16 yards he needs to reach 1,000, but he's unlikely to play the entire game Week 18.
Trevor Lawrence finally suffered an injury he can't play through, with the Jaguars officially ruling him out for Week 17.
CeeDee Lamb could have one of his biggest games playing against a Lions defense that's tougher against the run than the pass.
James Cook struggled against the Chargers on Saturday, but he dominated Buffalo's backfield snaps and touches to an extent previously unseen this season.
DK Metcalf could pose a major big-play threat to Tennessee's injury-challenged corner rotation.
If New England prioritizes defending Travis Kelce then the Pats might not have leftover personnel to cover Rashee Rice.
Ja'Marr Chase should keep rolling against a Colts secondary with poor boundary corner personnel.
The Saints are tougher on the boundary than in the slot, which should provoke a big game from Amon-Ra St. Brown.
CeeDee Lamb has been a menace from the slot, where Washington lacks the coverage personnel to defend itself.
Drake London is due for a bounce-back after no catches in Week 1, but Jaire Alexander could deny it anyway.
Dan Marcus looks at Sunday's divisional round and likes Joe Burrow, who has four 25-point FanDuel performances in his last nine games.